Tag: synthetic biology

  • Synthetic biology in the era of AI: From dominating nature to collaborating with it

    Synthetic biology in the era of AI: From dominating nature to collaborating with it

    Today’s post is a guest post by Christian Gude. He has a PhD in synthetic biology from the University of Nottingham (where we met when I was still doing synbio and RRI at the SBRC) and is now working at Phenotypeca Ltd as IP Analyst in a multidisciplinary role between science and intellectual property. In…

  • The language of life meets large language models

    The language of life meets large language models

    Between about 2014 and 2018 I was involved in the social and communications side of ‘synthetic biology’ as part of the Synthetic Biology Research Centre (SBRC) here at the University of Nottingham, which uses engineering biology approaches to understand and then modify industrially-relevant bacteria. I wrote my last blog post on synthetic biology in 2020.…

  • Understanding metaphors in the life sciences – a book review

    Understanding metaphors in the life sciences – a book review

    I recently wrote a review of a fascinating little book, Understanding Metaphors in the Life Sciences, by Andrew Reynolds. It appeared as part of the rather excellent series Understanding Life, published by Cambridge University Press and should be read in conjunction with another book in the series by Kostas Kampourakis entitled Understanding Genes, which came…

  • Minimal genomes, maximal assumptions

    Minimal genomes, maximal assumptions

    This is another guest post by Massimiliano Simons who is a postdoctoral researcher at the department of philosophy and moral sciences at Ghent University. He is also a member of the Working Group on Philosophy of Technology (WGPT) at KU Leuven, Belgium. *** Ten years ago the J. Craig Venter Institute announced the birth of…

  • Synthetic biology, engineering biology and responsible innovation

    Synthetic biology, engineering biology and responsible innovation

    Between about 2014 and 2018 I have been involved in the social and communications side of ‘synthetic biology’. I was especially interested in synthetic biology with relation to ‘responsible innovation’ or ‘responsible research and innovation’ or RRI (here are some blog posts). Since then other issues have pre-occupied my mind and I lost a bit…

  • Gene writing: Between art and nature

    Gene writing: Between art and nature

    In the past, I have written a bit about genomics, synthetic biology and gene editing, from the perspective of language and culture. So, when Matthew Cobb alerted me to a new thing called ‘gene writing’ at the beginning of July, I pricked up my ears. I told myself that I should write a blog post…

  • Gene drives and Trojan horses: A tale of two metaphor uses

    Gene drives and Trojan horses: A tale of two metaphor uses

    I was reading a recent article on gene drive entitled “Engineering bugs, resurrecting species: The wild world of synthetic biology for conservation” and came across this sentence about a so-called ‘Medea drive’: “This genetic Trojan Horse could then be used to spread elements that confer susceptibility to certain environmental factors, such as triggering the death…

  • Engineering biology? Sure! But which kind?

    Engineering biology? Sure! But which kind?

    This is a guest post by Massimiliano Simons who is a postdoctoral researcher at the department of philosophy and moral sciences at Ghent University, Belgium. *** Biology is a mess, not only the natural processes out there but also the science in the lab. Every biological rule seems to have exceptions and all biological laboratories…

  • A road called ‘gene drive’ and the road to ‘gene drive’: Trials and tribulations of media analysis

    A road called ‘gene drive’ and the road to ‘gene drive’: Trials and tribulations of media analysis

    As people might know, I enjoy doing media analysis of emerging biotechnologies, from cloning to gene editing and beyond. I have lately become fascinated with something called ‘gene drive’, a new genetic engineering technology that was brought to public attention around 2014/2015 at the confluence of two ‘events’: the outbreak of Zika and advances in CRISPR-Cas9…