Tag: genomics
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The Making Science Public blog: An introduction
I have now said farewell several times to my old university blogging platform, but I haven’t really started building up a new readership here. Newbies to the blog might wonder what the old Making Science Public blog was all about; what topics it covered before venturing to press the subscribe button….. As a gentle introduction…
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The genome as autoencoder: A new biological metaphor
I am just back from a walk thinking about Kevin Mitchell and Nick Cheney’s recent paper (preprint) on the genome as autoencoder, rather than a blueprint or recipe. This paper caused quite a stir and you can find a good summary in this post by Jessica Hamzelou for the MIT Technology Review. Walking along, I…
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A new language for a new biology? Let’s talk about it!
Philip Ball has written a book that introduces lay readers to entirely new dimensions of biology and reveals the intricate complexity of living organism: How Life Works. In the process of detailing the biological complexities of life, Phil also does something else; he scrutinises old ways if talking about life and takes apart old metaphors…
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Genes, trains and eureka-moments
I was in the process of writing a blog post on metaphors in genetics and genomics which was getting longer and longer and I had some personal stuff to deal with. So, I stopped. I might come back to this another time. In the process of writing, I discovered that trains have been quite an…
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Evelyn Fox Keller (1936-2023)
On 22 September 2023 Evelyn Fox Keller sadly passed away at the age of 87. She had been a theoretical physicist, a mathematical biologist, a feminist philosopher, a historian of science, and an inspiration to many across these fields. She integrated insights from all these fields creatively and critically, and, most importantly, she added some…
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Making Science Public 2021: End of year round-up of blog posts
We are coming to the end of a another pandemic year, and time seems to expand endlessness towards an uncertain horizon. That means quite a few of my blog posts this year were still devoted to covid and the pandemic, but I also wrote about genetics, climate change and some other incidental topics. As usual,…
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Post-Brexit gene editing regulation
Some of us are old enough to remember the controversies surrounding genetically modified or engineered foods and crops that raged in Europe (which included the UK) around the turn of the millennium. Some of us are even old enough to remember debates about recombinant DNA in the seventies (for those who don’t, I recommend Matthew…
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Eyes and organoids
I have written in the past about eyes and about organoids (but if you really want to know more about organoids, you should read Philip Ball’s How to Grow a Human). These two topics, eyes and organoids, recently came together. A few days ago, I saw tweets like this: “Small blobs of human brain grown…
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Maps, books and jigsaws: The human genome is back
I was recently messing about on the news database Nexis when I came across this pronouncement from 1982!! “Weissmann appealed directly to the delegates for an international basic-research fund to determine how genes function and their relationship to disease. With current technology, he declared, mapping the entire human genome would require some 50,000 man-years and…
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Genetics and genomics – when metaphors begin to matter
I remember in the not so distant past standing in the Wellcome Sanger Institute in Cambridge admiring the huge sequencing machines and chatting about public engagement with colleagues before giving a talk about genomics and metaphors. I also remember writing some things about gene editing and metaphor. In my mind all this related to basic…
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