Tag: synthetic biology
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Making science by publicity stunt: The case of the CRISPR babies
Science is supposed to be a public, systematic, consensible, evidence-based and collaborative enterprise. It’s also supposed to be carried out responsibly, not recklessly. Making science in public and making science public are complex processes. Making public science normally doesn’t consist in presenting fellow-scientists and members of the public with a ‘fait accompli’. This is however…
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Blueprint, a broken metaphor?
Three things came together that made me write this post: observing an increased discussion of the blueprint metaphor in genetics and genomics around the publication of a book called Blueprint, reading an old article by George Gamow, and reading a footnote in a forthcoming book by Philip Ball entitled How to Build a Human. The…
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Minimal biology
This morning (3rd November) I saw a tweet by @BrisSynBio announcing “Max Planck-Bristol Centre for Minimal Biology announced @BristolUni & @maxplanckpress partner to pursue game-changing research in the emerging field of #minimalbiology to address some of the most complex challenges in fundamental science”. I became curious and read the whole announcement, balking a bit at the pressreleasish…
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Anticipating public reactions to emerging sciences and technologies: Nano, synbio and AI
In around 2003 I woke up to nanotechnology because I was watching my son play a computer game that involved ‘nano-armour’. That pricked my curiosity. Later I came across a quote from Howard Lovy, then editor of Small Times: “Nanotechnology, independent of its development as a science, is spreading as a cultural idea and icon.…
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Phage and fiction
We have known about bacteriophages for over a century. I myself became vaguely aware of them around 2004 when I started to be interested in bacteria and antimicrobial resistance and later on when my mother had Clostridium difficile, a health-care associated infection related to antibiotic use. However, I never actually looked more closely at phages until Carmen…
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Synthetic biology: Modelling joys and fears brick by brick
Carmen McLeod, Stevienna de Saille and I recently published an article in which we used findings from a LEGO® SERIOUS PLAY® workshop to show that scientists’ (synthetic biologists’) views of risk and responsibility are much more ‘societal’ than one might expect. This means, involving them in a new form of science governance (RRI), which itself involves new…
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Bacteria, metaphors and responsible language use
A lot has been written about the war on bacteria, especially in the context of antimicrobial resistance. Some articles reflect on the metaphor of war in medicine and in microbiology more generally, others deal with the metaphors of bacterial communication and communities. A few papers look more closely at the way bacteria are anthropomorphised in the…
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Fermenting hope; fermenting hype?
When I first became involved with the Synthetic Biology Research Centre here at the University of Nottingham in 2014, I wrote a blog post in which I pointed to fermentation as one of its historical and intellectual roots. I called it ‘Fermenting thought’. Now, four years later, I have come across an article in The…
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In the shadow of Frankenstein: Mapping and manipulating genes and genomes
I was starting to prepare a talk for Pint of Science in May, for “The Body” strand, which this year here in Nottingham focuses on regenerative medicine and genetic engineering. It’s entitled “GMYou”. I know, it’s a long way off, but they needed a title and so I began to muse. In the end I…
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Catching a metaphor on the fly: ‘Greenfield genome design’
A week ago, something interesting washed up in my twitter stream, something a metaphor collector like me had to pick up and inspect. Andrew Hanson, an expert in metabolic engineering working at the University Florida, tweeted: “Excellent short 2016 piece from @claudiaevickers on #synbio platforms & the future of the microbial cell factory industry. Coins…
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